MDT 8200D: Molecular Biology of Cancer and Personalized Cancer Care 15-16

Owned by mcook
Feb 06, 2015
2 min read

The course is a review of the signaling transduction pathway that in “recent” years have become relevant to the study, but most important to the treatment of cancer and are the basis for the new paradigm of personalized medicine in oncology that Moffitt is championing. Morning didactic lectures as well as journal club presentations and faculty case presentations will be held in the Moffitt FOB1 Conference Room. Laboratory and specialty outpatient clinic rotations will take place at their corresponding locations in the Moffitt Campus.

 

The course consists of:

  • Basic science didactic lectures that describe the pathways and how they are relevant as targets to treat cancer (theory behind personalized medicine)
  • Didactic lectures that review the methods to analyze those pathways like IHC, FISH, gene analysis (microarray, DNA sequencing,), proteomics, etc… 
  • Rotations through some of the Moffitt laboratories to see first hand how these technologies work. 
  • Outpatient clinic rounds to see patients that are benefiting of the therapeutic options provided by these advances (practice and reality behind personalized medicine) 
  • Independent Research Project will consist of a project where the students will be first provided, in advance, seminal basic science articles as background references. Students will review the literature, identify, analyze and present clinical publications (minimum 2) relevant to the application of the personalized medicine concept to the care of the oncologic patient.
  • Interactive case presentation where the Faculty will present real cases of their own practice where the students will be asked to evaluate the patient (decision making of diagnosis and treatment) with real time faculty feed back (labs, x rays, scans, path, molecular studies).

Objectives

The goal of this course is the re-introduction to the pathophysiology of common solid and hematologic malignancies with emphasis on the basic scientific foundations (molecular and technologic) currently available to better understand them and treat them. Clinical methods sessions are to complement the basic science review.


Evaluation

Students will be evaluated on case presentations, journal club presentations, and interaction in clinic and didactic sessions.