MEL 8366: Adult Bone Marrow Transplantation

Dr. Michael Nieder and Faculty

Objectives

1. Have an understanding of the process of bone marrow transplantation and the associated immunobiology of immune recovery after ablative therapy and stem cell infusion
2. Identify the different types of transplantation (syngeneic, allogeneic, and autologous) and the diseases in which each type of transplantation may play a role in therapy
3. Identify common problems related to marrow transplantation such as cytopenias; infectious complications; nutrition and electrolyte imbalance; renal, cardiac, and pulmonary insufficiencies; graft vs. host disease; as well as outline current medical means to support patients until marrow and immune recovery

Methods

The student will assist hematology/oncology fellows in the primary care of patients undergoing high dose ablative therapy and bone marrow transplantation while receiving treatment in the Bone Marrow Transplant Unit at the Moffitt Cancer Center and Research Institute. The student will be expected to attend daily teaching and work rounds, as well as teaching and research conferences. The student's ability to perform and present thorough histories and physical exams will be evaluated. The student's verbal and written patient progress reports will also be evaluated daily at morning rounds. Faculty will monitor student progress and give ongoing feedback throughout the elective. No written examination will be given although an evaluation of the student's performance will be available at the end of each rotation.